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“Specialist Separations for the Pharmaceutical and Fine Chemical Industries”

Membrane Extraction Technology
Unit 25 Talina Centre
Bagleys Lane, Fulham
London, SW6 2BW
United Kingdom

Phone:
+44 (0) 20 7751 3153
Fax:
+44 (0) 20 7751 3154

 
  • Case Studies

Confidentiality is of paramount importance to MET. Consequently, not all case studies can be identified with actual company names.

Pharmaceutical Company

Used OSN to purify catalyst from product, while retaining the catalyst in a reuseable form, and reusing it to produce more product. Five batches of product were produced with just one batch of catalyst, resulting in proportionate cost savings. This application is currently undergoing pilot trials.
For more information, please ask us.

Electronic Materials Company

Used OSN to separate 300Da monomers from 3.5kDa polymers, in speciality electronics, thus enhancing product purification.
For more information, please ask us.

Catalyst Supplier

Used OSN to separate a ligand contaminant from a precious metal present in low concentration in a post-reaction stream. The ligand to metal ratio was reduced 10-fold after nanofiltration was applied, with 95% retention (i.e. very little loss) of the metal.
For more information, please ask us.

In-house research

Using OSN in research applicable to recovery of products from aprotic solvents such as DMF, DMAc, DMSO. A “put and take” membrane solvent exchange method allowed a toluene stream to be purified from 5 vol% DMF to 0.04 vol% DMF (99.2 % DMF removal) with 3 filtrations taking less than 1 hour start to finish, giving >95% yield of the high molecular weight solute dissolved in the toluene stream.
For more information, please ask us.

Nutraceutical Company

Used OSN to separate small undesirable fatty acids from desirable C18 to C22 fatty acids, from a health-boosting marine extract, thus enhancing product purity and minimising volume for downstream packaging.
For more information, please ask us.

MET-Specified Equipment in Operation
Rohm and Haas, Jarrow, UK.

Suggested a route for product recovery using coalescer technology. Carried out laboratory trials, constructed a pilot plant, and worked through installation and commissioning. Cost savings provided a payback of less than 12 months.

RohmHass_GIF1

 

The first process-scale MARS plant, operating at Degussa, Knottingley, UK

First process scale application of MET's MARS technology, to recover p-cresol. Costs of disposal reduced to 1/10th of competing technologies. Rapid laboratory-to-plant scale-up; from proof-of-concept in 1999 to process scale operation in 2002.
For more information, please ask us.

Deguss_GIF1

 

MET pilot plant operating at Solutia, Newport.
Solutia, Newport, UK

MARS was successfully used to recover phenol from one effluent streams. More than 90% of the phenol in the effluent was recovered, and importantly, was used to produce sales-grade product indistinguishable from product made with fresh phenol.

Solutia_GIF1

 

 

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